Applied Science and Biotechnology Journal for Advanced Research 2024-04-16T05:50:52+00:00 Prof. (Dr.) Sanjay Kumar Singh Open Journal Systems <p>Applied Science and Biotechnology Journal for Advanced Research is a Peer-Reviewed &amp; Refereed open access bimonthly international journal publishing original research papers / articles from all the fields of applied science and biotechnology subjects. Authors are encouraged to submit complete unpublished and original works, which are not under review in any other journals. </p> <p><strong>JOURNAL PARTICULARS</strong></p> <p><strong>Title:</strong> Applied Science and Biotechnology Journal for Advanced Research<br /><strong>Frequency:</strong> Bimonthly (6 issue per year)<br /><strong>ISSN (Online):</strong> <a href="" target="_blank" rel="noopener">2583-553X</a><br /><strong>Publisher:</strong> <a href="" target="_blank" rel="noopener">Vandana Publications</a>, Lucknow, India (Registered under the Ministry of MSME, Government of India with the registration number “UDYAM-UP-50-0046532”)<br /><strong>Chief Editor:</strong> Prof. (Dr.) Sanjay Kumar Singh<br /><strong>Copyright:</strong> Author<br /><strong>License:</strong> Creative Commons Attribution 4.0 International License<br /><strong>Starting Year:</strong> 2022<br /><strong>Subject:</strong> Applied Science and Biotechnology<br /><strong>Language:</strong> English<br /><strong>Publication Format:</strong> Online<br /><strong>Contact Number:</strong> +91-9696045327<br /><strong>Email Id:</strong><br /><strong>Website:</strong> <a href=""></a><br /><strong>Registered Address:</strong> 78/77, New Ganesh Ganj, Lucknow-226018, Uttar Pradesh, India.</p> A Study on Consumption of Energy & Health Drinks among Youth with Special Reference to Vapi City 2024-04-16T04:03:49+00:00 Jaya Tupe Hiral Vadgama Dr. Rajesh Kumar Pandey <p>Health drinks are liquids that give nutrition and hydration with minimal calories and sugar. Water is the best option for quenching thirst, however coffee and tea with no added sugars are good. While some studies suggest that energy drinks can improve physical performance and attention, they are also connected with serious health hazards, particularly among teenagers and young adults .So a survey was conducted to study the pattern of the consuming the energy and health drinks among the youth. The majority of the secondary data was gathered from online sources. The main primary source of data was a survey among the young people in Vapi city between the ages of 18 and 25. The aim of the study is to understand the concept &amp; essence of Energy Drink &amp; Health Drink. Also the Researchers aim to conduct the comparative analysis on consumption of energy &amp; health drinks among youth. The study encompasses the domain of Energy &amp; Health Drinks with its consumption among youth. The inferences are limited to the responses of a defined age group and may not be applicable to consumers at large. The conclusions may not apply to all consumers because they are restricted to the replies of a specific age group. The poll was performed using Google Forms, and 111 responses were received. The responses were gathered, processed, and summarized to produce informative data. The data was subsequently used to reach the final conclusion. The results are more indicative in nature rather exhaustive. Researchers have obtained a variety of results and findings regarding the youth and their drinking habits. The organizations in the field of Energy &amp; Health Drinks are the major beneficiaries through this study.</p> 2024-03-30T00:00:00+00:00 Copyright (c) 2024 Jaya Tupe, Hiral Vadgama, Dr. Rajesh Kumar Pandey A Study on Factors Attributed to Failure of Pharmaceutical Products 2024-04-16T05:50:52+00:00 Alkesh S. Mourya Dr. Rajesh Kumar Pandey <p>The Pharmaceutical Industry plays a pivotal role in healthcare by developing, manufacturing, and marketing drugs to treat a myriad of medical conditions. However, despite rigorous research, development, and testing processes, a significant number of pharmaceutical products fail to meet the expected standards or gain market acceptance. This study aims to explore the multifaceted factors that contribute to the failure of pharmaceutical products, focusing on the product life cycle as a framework for analysis. The product life cycle of a pharmaceutical product encompasses several stages, including research and development, clinical trials, regulatory approval, launch, and post-marketing surveillance. At each stage, various factors can influence the success or failure of a product. These factors range from scientific challenges and regulatory hurdles during the R&amp;D phase to manufacturing issues, competitive pressures, and post-market safety concerns.</p> <p>Through a comprehensive theoretical reviews and authors understanding of the subject, this study identifies key factors attributed to the failure of pharmaceutical products. These include but are not limited to <strong>Scientific Challenges:</strong> Inherent complexities in drug discovery and development, including target identification, drug design, and optimization, can lead to unforeseen efficacy or safety issues. <strong>Regulatory Hurdles:</strong> Stringent regulatory requirements and evolving guidelines can delay approvals, increase development costs, and limit market access for new drugs. <strong>Manufacturing Issues:</strong> Quality control failures, supply chain disruptions, and manufacturing inconsistencies can compromise the integrity, efficacy, and safety of pharmaceutical products. <strong>Competitive Pressures:</strong> Intense competition from generic drugs, biosimilars, and innovative therapies can erode market share and profitability, especially for products with limited differentiation. <strong>Post-Market Safety Concerns:</strong> Adverse events, drug interactions, and long-term side effects discovered after product launch can result in recalls, litigation, and damage to the brand reputation. By understanding and addressing these factors proactively, pharmaceutical companies can mitigate risks, enhance product quality, and improve the likelihood of success throughout the product life cycle. This study underscores the importance of comprehensive risk management, continuous monitoring, and adaptive strategies to navigate the complexities and challenges inherent in the pharmaceutical industry.</p> 2024-03-30T00:00:00+00:00 Copyright (c) 2024 Alkesh S. Mourya, Dr. Rajesh Kumar Pandey Enzyme Immobilization: Novel Approaches 2024-04-15T06:14:08+00:00 Radhika Kelkar Dr. Pallavi Patil <p>Enzyme enzymes are widely studied and explored areas due to their abundant potential to cater wide application range which makes researchers study more of this area. The high catalytic activity enabling ease in reactions formation of multiple products and byproducts or breakage of complex substances makes it an unavoidable option. However, the cost of pure enzyme increases the economic burden on the operations obstructing its full-fledged use. This leads to making enzyme restrict or immobilize within any inert matrix which can improve the reusability and also improve the tolerance against pH and temperature that can improve the activity of the enzyme. Many different enzyme immobilization approaches have been discussed in the following article.</p> 2024-03-30T00:00:00+00:00 Copyright (c) 2024 Radhika Kelkar, Dr. Pallavi Patil