The Pharmaceutical Industry plays a pivotal role in healthcare by developing, manufacturing, and marketing drugs to treat a myriad of medical conditions. However, despite rigorous research, development, and testing processes, a significant number of pharmaceutical products fail to meet the expected standards or gain market acceptance. This study aims to explore the multifaceted factors that contribute to the failure of pharmaceutical products, focusing on the product life cycle as a framework for analysis. The product life cycle of a pharmaceutical product encompasses several stages, including research and development, clinical trials, regulatory approval, launch, and post-marketing surveillance. At each stage, various factors can influence the success or failure of a product. These factors range from scientific challenges and regulatory hurdles during the R&D phase to manufacturing issues, competitive pressures, and post-market safety concerns.